Biologically inspired engineering design is an approach to design that espouses the adaptation of functions and mechanisms in biological sciences to solve engineering design problems. We have conducted an in situ study of designers engaged in biologically inspired design. Based on this study we develop here a macrocognitive information-processing model of biologically inspired design. We also compare and contrast the model with other information-processing models of analogical design such as TRIZ, case-based design, and design patterns.