We are pleased to report that this JCISE special issue on Artificial Intelligence (AI) in Design attracted about 40 submissions with more than a hundred co-authors! These numbers speak volumes about the importance and vigor of AI in Design as an interdisciplinary field of study. We hope that this special issue will add to the momentum of research into AI in Design. Only 14 papers were included in this special issue based on technical quality and fitness with the scope of this issue.